Searchable abstracts of presentations at key conferences in endocrinology

ea0013p333 | Thyroid | SFEBES2007

Neuropsychological abnormalities in overt and sub-clinical hypothyroidism improve but do not normalise following 3 months replacement with L-thyroxine

Correia Neuman , Mullally Sinead , Tun Tommy Kyaw , Phelan Niamh , Fitzgibbon Maria , O’Mara Shane , Boran Gerard , Gibney James

The neuropsychological mechanism underlying cognitive impairment in hypothyroidism is poorly understood. It is not known whether cognitive impairment resolves following L-Thyroxine (LT4) replacement. It is also unknown whether similar neuropsychological abnormalities occur in patients with sub-clinical hypothyroidism (SCH). To address these questions, we performed neuropsychological tests in 17 patients with hypothyroidism (age 45±3 years; mean±S.E.M.)...